Cold seal blister packaging
What is cold seal blister packaging?
Our expertise lies in developing packaging solutions for medications that require clear, high-quality, and custom-designed packaging. By offering tailor-made designs, we ensure that your product stands out in the market and meets all requirements and patient needs.
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Which formats are possible with cold seal?
Cold seal technology offers extensive design possibilities, making it suitable for a broad range of products, including:
- Blisters
- Syringes
- Medical devices
Whether you require packaging for high-value medications, specialty drugs, or medical devices, our cold seal solutions can be tailored to meet your specific needs regardless of the complexity.
What does the patient notice of cold seal?
We focus on creating packaging that not only protects the product but also enhances usability. Features such as easy-open mechanisms, clear instructions, and tamper-evident solutions improve the patient experience, leading to increased adherence and better health outcomes.
Clean material separation for easy recycling
One of the key advantages of our cold seal packaging is the ability to achieve clean material separation. After use, the plastic blister and the carton layers can be easily separated, allowing both materials to be recycled efficiently.
How does cold seal simplify the packaging process?
With pressure being the only sealing parameter, the cold seal process simplifies production by:
- Reducing setup times
- Quick and easy setup minimizes downtime.
- Minimizing changeover times
- Efficient due to no cooling down or heating up time.
- Enhancing scalability
- Suitable for both small and large production runs.
Support and flexibility
From the initial design concept to material selection and delivery of our cold seal blister cards, we offer full support throughout the packaging process. Our team works closely with you to develop a packaging solution that meets your specific needs. Whether you require assistance with a particular aspect of packaging or a complete end-to-end solution, we are here to help.
The services we offer for cold seal blister cards packaging include:
- Packaging components
- High-quality materials tailored to your product's needs.
- Packaging machines
- A range of equipment from manual to fully automated systems, for both cold seal and heat seal applications.
- Contract packaging services
- Complete packaging solutions managed at our GMP-licensed site, including serialisation, if required.
Whether your company requires just one of these services or the entire packaging process, we aim to provide flexibility. Our goal is to act as an extension of your team, ensuring that every project is executed efficiently and to the highest standards.
Expertise in cold seal blister packs
Our proficiency in cold seal technology and other specialized packaging methods allows us to handle complex projects, including those requiring child-resistant features in EU and US market.
Cold seal or heat seal: how do they compare?
| Cold seal | Heat seal | |
|---|---|---|
| How it seals | Pressure only: a water-based adhesive bonds two carton layers around the blister | Heat and pressure bond the lidding to the blister |
| Heat on the product | None | Brief exposure to elevated temperature during sealing; fine for most stable APIs |
| Energy on the line | Less than a heat seal line for the same throughput | Constant warm-up, hold and cool-down cycles |
| Set-up and changeover | No heating up or cooling down | Warm-up and cool-down time at every start and format change |
| After use | Paperboard and blister separate cleanly; the paperboard goes into paper recycling | In mixed-material packs the layers are fused |
| Best fit | Blister wallets for specialty medicines, biologics, hormone therapies, heat-sensitive drugs and clinical trial supplies | Traditional thermoformed foil blisters and very high-volume OTC products |
| At Ecobliss | Invented by our founder in 1995; chosen by many of our pharma customers | We run heat seal lines for the products that need it |
Cold seal packing in Echt
Packed in one of our GMP packaging rooms
Quality-checked in Echt
Cold seal in facts
- Cold seal was invented in 1995 by our founder Ron Linssen and Professor G. Wouters; the water-based adhesive is still produced in our own facility (our history).
- Many of our pharma customers choose cold seal.
- Packed in our GMP-licensed facility, with serialisation if required (contract packaging).
- Cold seal and heat seal machines, from manual to fully automated, available through blistermachines.com (pharmaceutical packaging machines).
Further reading: what a blister pack for medication is, the types of blister packaging and how cold seal packaging works. Source: European patent EP0866840 on Espacenet.
Frequently asked questions
What is the difference between cold seal and heat seal blister packaging?
Heat seal uses heat to bond the pack. Cold seal uses pressure only: the blister is clamped between two layers of carton with a water-based adhesive, so no heat is needed to seal and there are no heating or cooling times in the process.
Is cold seal suitable for pharmaceutical products?
Yes. Many of our pharma customers choose cold seal, for blisters, syringes and medical devices. We pack it in our GMP-licensed facility, with serialisation if required.
Is cold seal blister packaging recyclable?
The plastic blister and the carton layers are not sealed together, so after use they separate cleanly and both materials can be recycled.
Can you also supply child-resistant packaging?
Yes. For projects that need child resistance in the EU and the US, the Locked4Kids carton and Wallet Box are certified to ISO 8317 and to F=1 under US 16 CFR 1700.20. Test details are on locked4kids.com.
Can we run cold seal packaging in-house?
Yes. We supply cold seal and heat seal packaging machines, from manual shuttle machines to fully automated inline lines, with the tooling, validation documentation and on-site installation. You can compare all models on blistermachines.com.
Get a free cold seal wallet sample now!
- See how the contents are perfectly sealed in the wallet
- Take a look at the excellent printing outside and inside
- Only high-quality carton is used. The sealing is eco-friendly!
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